Erectile Dysfunction Drugs


Erectile Dysfunction Drugs26 May 2008 09:31 pm

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July 6, 2001 — Viagra, the little blue pill that made erectile dysfunction household words, may have some serious competition by this time next year when a new dysfunction pills
erectile dysfunction drug is expected to hit the market.

In clinical studies the experimental drug, called Cialis, improved erections in 85% of the men taking 20 mg of the drug and the drug’s effects last for 24 hours or longer. Viagra usually works for about four hours says Albert Yu, MD, senior director of clinical affairs at ICOS Corporation.

Cialis, pronounced “see-Alice”, is being developed as a joint venture between ICOS Corporation and Eli Lilly and Company. Late last week the manufacturers submitted a new drug application to the FDA. If the process goes smoothly “we expect to begin marketing by late in the second quarter of 2002,” says ICOS spokesperson Lacy Dysfunction erectile pill
.

From former Senator Bob Dole to Playboy founder Hugh Hefner, Viagra proved not only to be an effective treatment but has also caused a sea change in Americans’ attitudes about sexual dysfunction. Once considered a taboo subject, erectile dysfunction is now the subject of television, radio, and newspaper advertisements. For NASCAR fans, Viagra sponsors a race team.

Most men experience erection problems at some time in their lives, but about 30 million American men have chronic problems achieving erection. Erectile dysfunction, or ED as it is often called, can affect men at any age but becomes more common with age and 35% of men aged 60 or older have ED.

Buy sildenafil citrate the size of the market it is not surprising that the makers of Cialis are hoping that lightning will strike twice.

Yu tells WebMD that the new drug is very similar to Viagra, which is known medically as sildenafil. Both drugs, he says, inhibit an enzyme that affects the blood flow to the penis. “By inhibiting this enzyme, PDE5, blood flow is increased,” says Yu.

In studies reported at the recent American Urological Association meeting, 78% of men with mild to severe erectile dysfunction were able to complete intercourse after taking 20 g of the drug. Eighty-five percent of the men said they had improved erections, and 63% said they achieved normal erectile function when taking the drug.

Raymond Rosen, PhD, professor of psychiatry at the Robert Wood Johnson Medical School in New Jersey, tells WebMD that no clinical comparison of Viagra and Cialis has been attempted. “So any statements comparing the two are really hypothetical.” Rosen is a clinical investigator who has been involved in designing trials of Cialis and other drugs.

Rosen says Cialis “appears to have a rapid onset of action. You get an effect in about 30 minutes and it is effective up to 24 hours or possibly longer.”

At this point Rosen says the main advantage of Cialis is this long-acting effect. “People wouldn’t have to plan quite as carefully for when they would have intercourse. For example, if a man is planning to be with a partner all day Saturday, he could take the drug in the morning and have intercourse in the afternoon or evening. It’s less focused, more natural.”

Yu says the new drug appears to be “more specific for PDE5″ than Viagra is and this increased specificity means that the drug may cause fewer side effects than Viagra. Yu says that Viagra is generally well tolerated but that some men who take the drug get “blue tinge vision” because the drug also affects an enzyme called PDE6, which is involved in color perception in the eye. “We have not seen any color vision effects,” in any men treated in clinical trials says Yu.

Rosen agrees that the drug is well tolerated but he says that a small number of men will complain of headaches, flushing and, in a few cases, low-back pain when taking the drug. “But typically men don’t drop out of the studies because of side-effects,” says Rosen.

Cialis, like Viagra, should not be taken by men who are taking nitrates, says Yu. “This is because the drug has the same metabolic pathway as nitrates,” says Yu. He says, however, that the drug can be taken by men “who take any other type of heart or erectile dysfunction drugs
medication. There is no contraindication for men with heart disease.”

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Erectile Dysfunction Drugs25 May 2008 11:39 am

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–>

Feb. 8, 2002 — Move over, Viagra — here comes the competition. New drugs — and new interest in older methods — mean more erections for more men.

Viagra’s release in 1998 helped many of the 30 million U.S. men who have problems getting erections. Problem solved? Not yet. Viagra can’t help everyone. Some men can’t safely use it because they are on other 4allfreecom buy cgi gbid levitra link
, have other illnesses, or experience side effects. And for other men, Viagra just doesn’t work. For these men and their sex partners, claims that Viagra has cured erectile dysfunction have been misleading and frustrating.

But the huge research effort that Viagra spurred has already provided new insights into male sexual function — and new treatments, some of which will be available soon.

The Challengers

What’s wrong with Viagra? Nothing, for men in whom it safely works. But that hasn’t stopped two major drug companies from getting ready to release their own Viagra-like drugs. Eli Lilly and Company’s cialis generic pill viagra vs
drug, Cialis, may be ready to come to market later in 2002. Bayer’s offering, vardenafil, should be ready some time in 2003. They work much the same way as Viagra, but they should have fewer side effects. Whether they will prove safer or more effective remains to be seen.

Cialis works faster than Viagra — in about 15 minutes instead of half an hour. It lasts a lot longer, helping men get erections for 24 hours vs. the four-hour window Viagra provides.

Vardenafil — yet to get a catchy brand name — seems to work for men with many different types of erectile dysfunction. It seems to work especially well for men whose erectile dysfunction is related to diabetes. In one clinical trial, it worked even better for diabetic men with severe erectile dysfunction than for those with milder problems.

Other Oral Alternatives

Uprima was to have been the next treatment advance: By stimulating the brain rather than the muscles and nerves of the penis, Uprima placed under the tongue produced strong erections in most of the men on whom it was tested. It had preliminary approval from an FDA committee before it was withdrawn by the dysfunction pills
: A small number of people passed out after taking it. It’s available overseas, but plans for a U.S. release are on hold.

That hasn’t stopped Nastech Pharmaceutical Co. Inc. from developing a nasal version of the drug. In a preliminary study, it helped men with several different kinds of erectile dysfunction — and none of them passed out. Large-scale clinical trials are planned this year.

Yohimbine is another popular nerve-blocking agent used to treat this problem. It’s been available in the U.S. for many years, but carefully designed studies convincingly show that it isn’t very effective in promoting normal erection and sexual performance.

The amino acid arginine has been touted as a natural alternative to other erectile dysfunction drugs. When studied under rigorous conditions, though, results have been dysfunction erectile pill.

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Erectile Dysfunction Drugs20 May 2008 03:25 pm

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May 24, 2004 (New York) — Baby boomers are now set to revolutionize and revitalize the pharmaceutical industry — much like they did the diaper industry years ago — say antiaging experts speaking at a symposium on rejuvenation medicine in New York City.

Born between 1946 and 1964, the 80 million baby boomers change every market they enter and the pharmaceutical and nutraceutical industry will be no different. By 2025, at least 15% of Americans will be older than 65 and people older than 85 are the most rapidly growing segment of the population.

“The explosion in the U.S. of supplement usage occurred for many reasons including baby boomers who were are not happy with results of conventional therapies,” says wellness expert David H. Rahm, MD, president of VitaMedica Corporation in Manhattan Beach, Calif.

Catching More ZZZ’s

The first area they alter may be the treatment of sleeplessness.

“Sleep is such a huge problem and affects such a large percentage of our population that there is a lot of money to be made by the next pharmaceutical company to come up with a safe and effective agent,” Rahm says. According to the National Sleep Foundation, sleep disorders affect buy viagra canada
85 million people in the U.S.

The newer agents will reach beyond those currently available. “The problem with existing agents is tolerance. They stop working as well after a while, so you have to take larger doses to sleep,” he says.

In addition, he says, these medications have the potential to affect your liver in a negative way.

One promising drug currently awaiting FDA approval is Estorra, he says. In a recent study presented at the annual meeting of the American Psychiatric Association, Estorra cialis vs viagra
reduced the amount of time that older people with insomnia lie awake at night. Estorra, which slows brain metabolism and activity, also helped elderly people with insomnia fall asleep faster and cut down on daytime drowsiness.

“This is a very promising agent,” Rahm says.

Move Over Viagra?

Another thing aging boomers won’t give up any time soon is their sex life.

However, Rahm says, that efforts to develop drugs that treat female sexual dysfunction will all fall short. Unlike male sexual dysfunction, “female sexual dysfunction is not a very promising area for the development of drugs because sexual function in women is very sophisticated and a complicated issue that goes far beyond pharmaceutical agents,” he says.

Memory Menders

Drugs aimed at alleviating the cognitive function that comes along with normal aging will also be warmly welcomed by the baby boomer sect, Rahm predicts.

Currently available drugs such as Aricept (donepezil erectile dysfunction answers
) “are targeted toward people with early signs of Alzheimer’s disease where there is true disease and you are trying to alter the course and that’s very different from a healthy patient with cognitive manifestations of aging in whom you want to improve his or her mental function,” he explains.

These agents may be pharmaceuticals or they may be nutraceuticals, he predicts.

So how does plastic surgery fit into all of this?

It’s simple, “baby boomers will want to look younger if they live longer and feel better,” says Brian M. Kinney, MD, a plastic and reconstructive surgeon based in Los Angeles.

James H. Carraway agrees which is why he says age management should become part of some plastic surgery practices.

“Plastic surgery can give a more a youthful look and appear to turn the clock back … add this to other treatments directed to appearing and feeling more youthful and it is a great combination,” he says.

Age management can address weight gain, nutrition, exercise, supplements, hormone replacement, cognitive assessment, stress management, hair and cosmetics, and cosmetic surgery procedures.

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Erectile Dysfunction Drugs19 May 2008 01:22 pm

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Nov. 21, 2003 — Look out, America, here comes “Le Weekend.” That’s what the French are calling the newest erectile dysfunction drug approved by the FDA.

It’s called Cialis — pronounced “SEE-Alice.” Like Viagra and Levitra, it doesn’t make a man’s penis erect. Instead, the drugs make it possible for a man who’s had trouble getting and keeping erections to have one when he’s sexually aroused.

Viagra starts working in about half an hour, and its effect lasts for about four hours. Levitra has about the same window of effect. Cialis gets to work a bit faster — a third of men respond in 15 minutes — but lasts for 36 to 48 hours in some men (but by no means all).

Urologist Gerald Brock, MD, associate professor at St. Joseph’s Health Center in London, Ontario, is past chairman of the Canadian Male Sexual Health Council. He’s treated many patients with Viagra and, in clinical trials, with Cialis and Levitra.

“Cialis will be an important addition to the way we treat men with erectile dysfunction,” Brock tells WebMD. “It provides an opportunity for many men to take a pill and have a window of opportunity that extends 36-48 hours where they will have a significant improvement in their sexual function.”

Cialis is ed medicine
by Eli Lilly and Co. and ICOS Corp. Lilly is a WebMD sponsor.

There’s another important difference between the three drugs. Viagra takes longer to work if taken after a high-fat meal. Cialis and Levitra can be taken on a full stomach regardless of what you’ve eaten.

Chad Ritenour, MD, teaches urology at Atlanta’s Emory University. He says lots of patients will want to try the new drug.

“I tell patients it is going to be like Pepsi vs. Coke — get ready for the viagra for woman study
blitz,” Ritenour tells WebMD. “But I don’t think anybody can say one works better than the other. Each drug probably will work better for some patients than for others.”

How They Work

All three drugs work the same way. They block an enzyme called PDE-5, a natural chemical that’s part of the chain of chemical messages that tell a man’s erection to go away. Brock says that there’s more PDE-5 in the penis than in other areas of the body, so the drugs have a pretty specific effect.

However, Viagra and Levitra ed meds
block a sister chemical — PDE-6 — that affects color vision. Some men report a slight bluish tinge to their vision; some become more sensitive to light. These effects go away in a few hours. Cialis doesn’t seem to have this effect.

Cialis has a different side effect. It blocks PDE-11, which is found in many parts of the body including the smooth muscles of the internal organs, the heart, skeletal muscles, the pituitary gland, and in the germ cells of the testes. So far, Cialis seems to have no harmful effect on these tissues. But PDE-11 may be involved in Cialis’ most troublesome side effect: Back pain. According to a spokesperson for Lilly ICOS, back pain was reported by 5% of patients taking 10 mg of Cialis and 6% at the 20 mg dose. Patients taking placebo reported back pain 3% of the time.

Which one do men like best? In a recent head-to-head-to-head study of all three drugs taken at the recommended starting dose by men with erectile dysfunction:

  • 47% preferred Levitra.
  • 34% preferred Viagra.
  • 19% preferred Cialis.

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Erectile Dysfunction Drugs18 May 2008 01:05 pm

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Nov. 2, 2004 — The FDA is warning men to steer clear of two dietary supplements promoted and sold on the Internet for treating erectile erectile dysfunction drugs
and enhancing sexual performance.

The FDA says the supplements, sold under the names Actra-Rx or Yilishen, actually contain an active prescription ingredient that could cause serious sildenafil citrate and discount in some men.

The agency has also issued an alert instructing FDA officials to stop the importation of Actra-Rx and Yilishen.

A chemical analysis published earlier this year in The Journal of the American Medical Association showed that a sample of Actra-Rx sold by Body Basics of Los Angeles contained a prescription-strength amount of sildenafil. Sildenafil is the active ingredient in the prescription drug Viagra, which is approved by the FDA for the treatment of erectile dysfunction.

In its own tests of Actra-Rx, the FDA also found that the supplement contained prescription-strength sildenafil.

Dangers of Sexual Supplements

FDA officials say an interaction between sildenafil and certain prescription drugs containing nitrates, such as nitroglycerin, or nitrates found in illegal drugs may cause a dangerous lowering of blood pressure.

People with high blood pressure or heart disease are often prescribed drugs containing nitrates. Because erectile dysfunction is a common problem among men with these conditions, officials say taking Actra-Rx or Yilishen could increase the risk of serious and potentially levitra sample
side effects.

Officials say anyone buy now viagra
erectile dysfunction should see their doctor to discuss treatment options and should not take dietary supplements that claim to treat the condition.

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Erectile Dysfunction Drugs17 May 2008 12:29 pm

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Erectile dysfunction (ED), commonly known as impotence, can be
troubling, even erectile dysfunction
, to a man. But it can be equally so for his partner
as well, as Beth (who asked that her real name not be used) found out.

“It really ed tablets
a relationship,” says Beth, who
recently broke off an engagement with a man who suffers from ED. It’s
especially difficult, she adds, if the man blames his partner, as her fianc
did.

“Even though my fianc admitted that he had always had
generic sildenafil citrate with his erections,” says Beth, “he tried to tell me that
it was my fault. After you hear that enough, you start to believe it, and it
can really affect your self-esteem.”

That’s not unusual, says Karen Donahey, PhD, director of the
Sex and Marital Therapy Program at Northwestern University Medical Center in
Chicago. “A woman may struggle with the notion that she’s no longer
attractive to her man,” says Donahey. “Even if the man assures her it’s
not true, there’s still a worry there.”

The stronger a woman’s self-esteem is, says Donahey, the less
threatened she’ll feel by her partner’s erectile dysfunction and the more
supportive she’ll be able to be.

ED Is Not Uncommon

“It’s important for both men and women to realize that ED
is not at all uncommon,” says Donahey. Indeed, most estimates suggest that
at least 50% of men in the U.S. experience some form of sexual dysfunction at
some point in their lives. ED is one of the most common male sexual problems,
affecting an estimated 30 million men in the U.S. and exercise and health
140 million
men worldwide.

Though ED may indeed be common, it’s still stressful, and in a
study conducted by Pfizer (which makes the impotence drug Viagra), research
showed that most women, where their quality of life is concerned, rank ED
higher in importance than menopausal symptoms, infertility, allergies, obesity,
and insomnia.

In a series of focus groups, Pfizer researchers found that when
faced with ED, women — and their partners — either generic sildenafil citrate that they had
a problem or denied the existence of a problem. “While this may be
intuitive, our research showed that there are differences in how women
acknowledge the problem and how they deny the problem,” says Janice Lipsky,
PhD, senior marketing manager for the sexual health team at Pfizer.

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Erectile Dysfunction Drugs16 May 2008 10:19 am

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Men and women have sought aphrodisiacs, agents that arouse or
increase sexual response or desire, since the beginning of time. Aphrodisiacs
may well be the one thing that crosses all barriers — race, culture,
ethnicity, age — making it unanimous: We all want to have better sex.

If you looked hard enough, you could find an authority for
almost any folk belief about the stimulating properties of a substance. And
although the Food and Drug Administration has determined that all these
non-medicinal approaches are ineffective, people still follow their heart’s
desire in search of the perfect catalyst for love.

Foods

One category of foods that were thought to be aphrodisiacs are
foods that resemble genitalia. Eggs and caviar may come to mind, as well as
asparagus, celery, and onions. Clams and oysters also lay claim to aphrodisiac
qualities because of their shape and texture. Oysters, in fact, are high in
zinc — a nutrient that was lacking in people’s diets at one time; eating them
could improve a cialis vs viagra
deficient diet, thus improving a person’s overall
health and increasing his or her sex drive.

Spicy foods have long been considered to be sexual stimulants.
There is some scientific truth to this claim in that foods that are heavily
spiced often contain capsaicin, the active ingredient in cayenne pepper. Eating
capsaicin can cause a ed meds
response — increased heart rate and
metabolism, sometimes even sweating — that is quite similar to the physical
reactions experienced during sex.

Okra is another reputed vegetable of love. Rich in magnesium,
it’s a natural relaxant. It’s also full of iron, folate, zinc, and vitamin B,
all nutrients that keep your sex organs healthy and happy. A little gumbo,
anyone?

Herbs

An herb very commonly associated with love is ginseng. Some say
ginseng is an aphrodisiac because it actually looks like the human body. (The
word ginseng even means “man root.”) Studies have reported sexual
response in animals who have been given ginseng, but there is no evidence to
date of ginseng having any effect on humans.

Yohimbe is an herb found in Africa and India that for centuries
has been thought to possess aphrodisiac qualities. It works by stimulating
nerve centers in the spine, thereby improving the capacity for erection without
increasing sexual excitement. These days, some call it the herbal Viagra.
Unfortunately, there are side effects to taking this herb, which include
anxiety, weakness, overstimulation, paralysis, and hallucinations. Sounds like
a large price to pay for the erectile dysfunction pills
of better sex, don’t you think?

Spanish Fly

No discussion of aphrodisiacs would be complete without mention
of Spanish fly, the most legendary of the love drugs, but also the most
dangerous. Spanish fly, or cantharides, is extracted from dried beetle dung.
Reported sexual excitement after taking Spanish fly stems from its ability to
irritate the urogenital tract, causing a rush of blood to the genital area. And
that’s not the down side! Spanish fly is a poison that burns the mouth and
throat, and can cause urinary infections, scarring of the urethra, and in some
rare cases, death.

Organic Aphrodisiacs

Aside from the groundbreaking release of Viagra, there have
been few laboratory studies on aphrodisiacs. To date, the only evidence of any
organic aphrodisiacs has been anecdotal and subjective.

Sights, sounds, and scents within your reach are the best
precursors for a romp in the hay. Nothing can compare with the sight of your
partner’s lips parted in a smile — or the sound of those three words, “I
love you.” Combined with a healthy dose of mind candy (your imagination),
you’re well on your way to a fabulous night of sexual exploration.

Other Reputed Aphrodisiacs

Rhinoceros horn
Deer antler
Chocolate
Truffles
Clove
Sandalwood
Alder bark
Damiana
Gypsyweed Rose petals
Patchouli
Muira Puama
Catuaba

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Erectile Dysfunction Drugs15 May 2008 01:59 am

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Nov. 2, 2000 — Say “erectile dysfunction” these days,
and the response is likely to be “Viagra.” Such is the power of
advertising. But there was a time, not that long ago, when psychotherapy was
the mainstay of treatment for what was then known as “impotence.” Has
it become outdated or irrelevant?

It shouldn’t be, say the New England Research Institutes. In a
study published in the American Journal of Epidemiology, the Watertown,
Mass.-based organization analyzed nearly 800 men of whom more than 160 had
erectile dysfunction, and found that men who are submissive are much more
likely to develop erectile dysfunction than those who are not — and that
problem can’t be cured by the little blue pill.

Regardless, psychologists say they are feeling the pinch of the
Viagra revolution. “There’s a very significant drop in the number of men
who come into a therapist now for ED erectile dysfunction,” says Paul
Tobias, PhD, a psychologist in private practice in Santa Monica, Calif.
“Their primary response is to see an internist and get Viagra prescribed –
or not prescribed. As a psychologist, this seems like you deal with the
symptom, not the cause. It’s very easy to use a Band-Aid — but quite often it
doesn’t take care of the root cause.”

But even Tobias admits that Viagra can sometimes be the answer
even when a psychological problem is the primary cause of a failed erection.
Take the case of a man with ed tablets
anxiety — perhaps the most common
psychological cause of erectile dysfunction. If you increase performance by
prescribing Viagra, then the anxiety part of the equation disappears.

But, Tobias says, Viagra is not a fix-all — perhaps especially
when the problems involve younger men. “Younger couples need to work with
someone because the issues are quite often buried — issues of power,
dominance, virility. Often ED is just a symptom of a conflict that exists
between a couple.”

Psychologist Warren Edwards, PhD, remembers the days when
erectile difficulties were thought to be connected to males’ too-early viewing
of a vagina. “In the early 1960s, we talked seriously about that stuff. Now
we’re more recognizing that things have changed — and we’re once again going
back to the idea there’s some organic component in most men’s erectile
dysfunction.”

Edwards, a staff therapist with the Mercy Hospital in Des
Moines, Iowa, points out that the reverse scenario also is true in many cases
– where otherwise soft viagra
healthy men develop erectile dysfunction for
physical reasons, and then develop psychological problems. “I’ve
worked a lot with men in their middle years, and typically they would have some
organic contribution. Maybe they were overweight or had a pain in their
back.” Sex was generic online pharmacy viagra
for these men, he says, so they would resort
to trying to get it over with quickly. That would lead to problems. “If
you’re 60 years old and trying to have sex in a hurry, you’re probably going to
fail.”

Edwards says it’s not new that men with erection problems
consult their medical doctors first. “They always did go to the medical
doctors. Treat erectile dysfunction the best weren’t their first choice. It was in the hope there
was something their doctors could give them. And now there is.” But, he
says, many older couples he’s seen have found a simpler, less expensive (and
safer) solution: a good lubricant.

Tobias suggests that while there may be value in Viagra, the
ads for the drug encourage indiscriminate use: “The ads themselves lead to
tremendous expectations, and Viagra may not even be the answer.” He says:
“No matter how many caveats you put in the ads, all the man hears is the
opening statement: ‘Here’s the solution to your problem.’” Maybe that’s
true, Tobias says — and maybe not.

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Erectile Dysfunction Drugs14 May 2008 12:34 am

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June 9, 2000 — It made her feel as tingly as a high school girl, says the
44-year-old New York marketing executive.

The executive, who spoke on condition of anonymity, says she tried a topical
Viagra cream because she sometimes levitra vs cialis
periods of lower sexual desire.
The cream is applied 15 to 20 minutes before intercourse, and the result is
“a tingly sensation in the vaginal area,” she tells WebMD. “It made
me feel like I was back in high school — very erotic and arousing.”

The idea that Viagra might be able to help women, following on the heels of
its much-touted success in men, is bringing the topic of female sexual
dysfunction out of the closet and into everyday conversation. So is the medical
tag team of Laura and Jennifer Berman, PhD and MD respectively, who are helping
to shatter the myth that women do not have the same sort of sexual responses,
needs, and problems with desire and arousal as men do.

The Berman sisters have made television appearances on Larry King
Live
and other talk shows, and are often quoted in newspaper and magazine
articles about female sexuality. At the annual Congress on Women’s Health and
Gender-Based Medicine, held recently in Hilton Head, S.C., they spoke about
their recent work and women’s sexual issues in general.

Laura Berman is a sex therapist who, with her sister, Jennifer, a urologist
at the Women’s Sexual Health Clinic at Boston University Medical Center in
Boston, is exploring both the physical and cure dysfunction erectile herbal aspects of low sexual
desire.

A recent survey looking at women ages 18 to 59 showed that 43% of women have
complaints about sexual function, Laura Berman says. She tells WebMD that women
need to tell their physicians when they feel that their sexual functioning is
not what it should be.

“If it’s something that’s missing for them, they should ask their
physicians about it — whether it’s complaints of lack of interest, whether
it’s lack of arousal, sensation, not being able to reach an orgasm, or the
intensity of the orgasm,” she says. This is especially true if the woman’s
sex life was OK before and suddenly changed.

Low desire, sometimes called hypoactive sexual desire disorder, is one of
women’s most common sexual complaints. To be considered a medical problem,
according to the American Foundation of Urologic Diseases, this lack of desire
must be “persistent and pervasive” and cause a woman personal distress.
This last point, Laura Berman says, is most important — “in other words,
one woman’s inadequate orgasm is another woman’s dream orgasm.”

The Bermans have been looking at what they say is a subset of low sexual
desire — low arousal disorder, which they define as an inability to achieve
adequate lubrication, swelling, and sensation (separate from orgasm).

One of the biggest problems in treating female sexual dysfunction is the
fact that so many factors are involved — the physical aspect, relationship
issues, self-esteem issues. “You can’t just send a woman home with
medication,” Jennifer Berman says.

This may be one reason why Viagra does not seem to hold the same promise for
women as it does for men. But in their research, the Bermans say, they have
found that Viagra does work well for a certain group of women, especially those
who don’t suffer from syndromes associated with chronic sexual abuse.

They studied 35 women, 23% of whom had unresolved sexual abuse issues, and
assessed them in terms of vaginal lubrication, quality of sensation, ability to
reach orgasm, and sexual satisfaction. Viagra appeared to bring about
soft viagra
in all areas in 60% of the women who had no unresolved problems
related to abuse, and in 29% of those with chronic abuse issues.

Still, the drug is not for everyone. A 48-year-old New York health writer,
who spoke to WebMD on condition of anonymity, had a bad experience.

“I have panic disorder, so I take medications for that, and as a side
effect of that medication, I experience delayed orgasm,” she tells WebMD.
Her doctor suggested Viagra in pill form.

“So I tried it,” she says. “It was a very unpleasant experience.
My blood pressure dropped. I got a killer headache, and my face turned bright
red, and I had panic attacks — all without an orgasm.”

So instead, she reduced the amount of medication she was taking for the
panic disorder, and her sexual function has since improved.

Vasoactivate drugs such as Viagra continue to be studied in the U.S. to
determine which women will most benefit from them, Jennifer Berman says. Maybe
a drug like Viagra is not the same magic bullet for women as it is for some
men, but perhaps in combination with other drugs or hormones, it may still have
its place in the female sexual pharmacopia. Erectile dysfunction answers
also are looking at
testosterone pills and creams for women.

In their clinic, the Bermans use actual physical measurements to help assess
sexual problems. Jennifer Berman measures genital blood flow, vaginal pH (the
pH increases with sexual stimulation), inner vaginal pressure changes, and how
well the genitals perceive movement. Of the latter, she says that often, women
complain of “feeling asleep” in their vaginas or labia.

These measurements are important because assuring a woman there is a
physical reason for her lack of arousal or desire takes away the “it’s all
in your head” aspect.

When taking these measurements, the Bermans go so far as to choose erotic
videos that are more appealing to women. Those shown to men usually have little
if no effect, they say. The main difference, Laura Berman says, is “they
actually have a plot.”

The main point for women to take into the bedroom, she tells WebMD, is that
they should be advocates for their own sexual needs. If there is a physical
problem, it needs to be addressed. But women also need to learn about their
bodies and take responsibility for teaching their partners how to sexually
satisfy them, she says.

“Some women are under the impression that they will be perceived as some
sort of harlot if she shows him, describes to him, or instructs him how to
sexually satisfy her,” she says. “That’s really more of a myth than
anything else, and most men really do appreciate it.”

Vital Information:

  • A recent survey showed that 43% of women have sexual function complaints,
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Erectile Dysfunction Drugs12 May 2008 11:15 pm

erectile dysfunction drugs

May 2, 2000 (Atlanta) — One of the major concerns about Viagra is whether
the impotence drug is suitable for patients with heart disease. And those
taking drugs known as nitrates for heart conditions already are warned not to
use the distinctive blue pills. Now another treatment for impotence has been
tested on men suffering with impotence and heart disease, and the results are
encouraging.

At the same time, neurologists in California are finding that Viagra gives
patients with Parkinson’s disease substantial relief from uncontrolled movement
symptoms associated with the brain disorder.

The new drug, Uprima, was studied in nearly 1,500 patients, about 225 of
whom had a history of heart disease, over the course of two months. After
trying various doses of the drug, the researchers found that at the dysfunction erectile penile
dose, about one in two attempts at intercourse were likely to be successful.
Those not receiving treatment had successful intercourse in less than one out
of four attempts.

The research, paid for by the drug dysfunction erectile
TAP Holdings, was presented at a
urology conference here this week.

Uprima is taken by placing it under the tongue and allowing it to be
absorbed into the bloodstream. It was recommended for approval by an advisory
panel to the FDA last month, even though there were concerns about Uprima’s
side effects. About one-third of those taking the drug at a high dose suffered
from nausea or dizziness.

It’s still not clear how Uprima may interact with longer-acting nitrates,
although there is some indication that the combination may lead to fainting or
dangerously low blood pressure. That side effect may have proven lethal to some
nitrate patients who tried Viagra.

However, lead investigator for the new study, Eugene Dula, MD, says Uprima
does appear safer for many heart patients. Dula is medical director of the West
Coast Clinical Research in Van Nuys, Calif.

Dula tells WebMD that Viagra or Uprima should be fine for patients not
taking nitrates but who take one or two drugs for high blood pressure. If they
are on nitrates, especially the erectile pill variety, Dula thinks Uprima may be
a good option for these patients. He also says the short-acting nitrates
haven’t caused a profound dip in blood pressure, and that the FDA is taking a
hard look at the longer-acting versions. Other doctors feel that Uprima may be
a useful alternative for patients trying to cope with heart disease and
impotence.

“The nitrate studies are very small with Uprima. There’s about a 10%
incidence of blood pressure changes. They’re not of the magnitude that occur
with Viagra and nitrates, but they are somewhat concerning,” John Mulhall,
MD, assistant professor of urology at Loyola University Medical Center, tells
WebMD.

There also are questions about Uprima’s effectiveness since a relatively
high percentage of those getting placebo treatments also were able to achieve
an erection. “The patients that were entered into the study may not have
had severe sexual dysfunction to start out with,” says Patrick Walsh, MD,
chief of urology at Johns Hopkins Medical Institutions in Baltimore.

Uprima is thought to work by stimulating that area of the brain responsible
for causing erections. Interestingly, it’s also been used to treat Parkinson’s
disease.

Now a new study suggests that Viagra may prove beneficial to people with
Parkinson’s disease. Symptoms of Parkinson’s include shaking, poor balance,
muscle rigidity, and dyskinesia, or abnormal, involuntary muscle movements.

In this study, presented at a neurology conference in San Diego, seven of
nine Parkinson’s patients treated with Viagra experienced a significant
improvement in dyskinesia, with three patients reporting a complete resolution.
The benefits lasted for as long as they remained on the drug and returned when
the drug was discontinued. The patients continued taking their other medicines
while on Viagra and experienced no worsening of their symptoms. Flushing of the
face, reported by one person, was the only side effect, and there was no change
in sexual function.

Neurologist David M. Swope, MD, who conducted the trial, tells WebMD he was
intrigued when one of his patients, a 60-year-old man, said his Parkinson’s
symptoms improved after he started taking Viagra for impotence. Swope theorizes
that the drug’s effects may resemble those of dopamine, a chemical in the brain
and nervous system known to be decreased in Parkinson’s patients. Swope is
assistant professor of neurology at Loma Linda University in Loma Linda,
Calif.

“I was surprised it worked in these patients as well as it did,” he
says. “I ? wasn’t expecting it to be effective in these patients.”
Swope warns that these findings are “very, very preliminary. We need more
evidence that it actually works before it is used routinely.” He is now
designing another study to test the effects of Viagra more carefully. “I
think the role of Viagra has yet to be defined, but dysfunction pills
this might be
a new approach to treatment.”

Vital Dysfunction erectile pill
:

  • A recent study suggests the drug Uprima may safely treat impotence in
    patients who also have heart disease.
  • A Uprima researcher says the drug seems safer than Viagra for patients who
    are taking nitrates for their heart conditions. Doctors still don’t know the
    long-term effects of taking Uprima and nitrates together.
  • Researchers also are testing how Viagra might help people with Parkinson’s
    disease control some of their movement problems.

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